A rare case of neonatal-onset infantile myofibromatosis with metastatic recurrence in adulthood

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Infantile myofibromatosis : report of a rare disease *

The pathogenesis of generalized fibromatosis still remains unknown, despite reports on association with estrogen receptors. This disease is classified into three types as follows: solitary fibromatosis, congenital generalized fibromatosis without visceral involvement, and congenital generalized fibromatosis with both cutaneous and visceral involvement. In most cases, the disease is sporadic, bu...

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Infantile myofibromatosis*

Infantile myofibromatosis is a mesenchymal disorder characterized by the fibrous proliferation of the skin, bone, muscle and viscera. It is the most common fibrous tumor in childhood. We present a newborn with skin and bone disease without visceral involvement, who showed good response to vinblastine and methotrexate. Clinical features, etiology, diagnosis, and treatment are reviewed.

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Infantile Myofibromatosis

Infantile myofibromatosis (IMP) is a rare tumour with a wide spectrum of disease activity ra a solitarY cutaneous nodule through to a multicentric form ,vith widespread visceral involveluent. R is charactelised by its unique ability to spontaneously regress and has a typical histological appearance of a~tin-positivefibroblasts arranged in whorls or fascicles and vessels in a pericytomatous patt...

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Infantile myofibromatosis.

Infantile myofibromatosis (IMF) is a rare tumour with a wide spectrum of disease activity ranging from a solitary cutaneous nodule through to a multicentric form with widespread visceral involvement. It is characterised by its unique ability to spontaneously regress and has a typical histological appearance of actin-positive fibroblasts arranged in whorls or fascicles and vessels in a pericytom...

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Congenital Infantile Myofibromatosis: A Case Report and Review of Literature

Received March 29, 2003 Abstract Congenital infantile myofibromatosis is a rare disorder with multiple fibromatous tumours in skin, bone, muscle, viscera and subcutaneous tissue presenting in early infancy. Multiple lytic bone lesions and vertebra involvement are also common, mimicking the clinical picture of metastatic tumours. However, it is a disease with variable prognosis depending on the ...

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ژورنال

عنوان ژورنال: Archive of Clinical Cases

سال: 2018

ISSN: 2360-6975,2360-6975

DOI: 10.22551/2018.19.0502.10124